Marco Zanuso was born in Milan, when he lives and works, and he graduated in Architecture in Florence, with an experimental thesis on radical architecture and its main characters: Superstudio, Michele De Lucchi, Andrea Branzi, Ufo, Mendini ed Ettore Sottsass
He spent long periods in France, Spain, and especially in the United States discovering and getting involved in the architecture of Arcosanti, Land Art, Berkeley, and the first experiments on solar energy. In Vienna with artists and architects founded Rastlos, a group that performs advice and research on issues of urban planning, organizing exhibitions and seminars.
After Florence he worked with his uncle Marco Zanuso Senior both on architecture and design.
In 1991 he opened the studio in Milan, with Daniel Nava, that deals with product design, architectural design of residential buildings, offices interiors, private homes and outfitting exhibitions.
As designer he worked with various companies including Memphis.